Vitamin C Promotes Epidermal Proliferation by Promoting DNA Demethylation of Proliferation-Related Genes in Human Epidermal Equivalents

Vitamin C Promotes Epidermal Proliferation by Promoting DNA Demethylation of Proliferation-Related Genes in Human Epidermal Equivalents

Vitamin C Helps Skin Grow by Rewriting Its Instructions Most people know that vitamin C is good for your skin. It’s often found in skincare products and is known to help with things like brightening your skin and making collagen, which keeps skin firm. But a new study shows that vitamin C actually does something even more amazing, it helps your skin grow better by turning on special instructions inside your skin cells. These instructions tell your cells to divide and make more skin, which helps your skin stay thick and healthy. The researchers wanted to know exactly how vitamin C helps skin grow. To find out, they created lab-grown skin that’s very similar to real human skin. Then, they added vitamin C to it and watched what happened. They discovered that the skin became thicker, and more new skin cells were being made. This showed that vitamin C was helping the skin to grow. But the scientists didn’t stop there, they also wanted to understand how vitamin C was doing this. Inside every cell, there’s a set of instructions, like a recipe book, that tells the cell what to do. But sometimes, parts of this recipe book are “turned off,” like pages that are stuck together and can’t be read. Vitamin C helps “unstick” these pages, so the cell can read them again and follow the instructions to grow. When vitamin C was added, the skin cells turned on certain instructions that told them to grow and divide. The skin became thicker because more cells were being made. The researchers also tested what would happen if they blocked the effect of vitamin C, and sure enough, the skin didn’t grow as much. This proved that vitamin C was playing a key role. They found 12 special instructions (or “genes”) that were turned on by vitamin C. These instructions all had to do with helping the skin grow. As we get older, our skin becomes thinner and doesn’t heal as well. That’s because the cells don’t grow as fast as they used to. This study shows that vitamin C might help solve that problem. By turning certain cell instructions back on, it helps the skin grow more, stay thick, and possibly heal faster. This could be useful not just for skincare products, but also for helping people with thin or damaged skin, like older adults or people recovering from injuries. We usually think of vitamin C as something that helps us stay healthy or fight off colds, but this study shows it also helps your skin grow stronger, starting from deep inside the cells. It’s like giving your skin a reminder of how to grow and repair itself. So the next time you hear about vitamin C in a skincare product, remember, it’s not just working on the surface. It’s helping your skin from the inside out. 

 For more information : https://pubmed.ncbi.nlm.nih.gov/40262671/